# Cohorts

## Introduction to Cohorts

ICA Cohorts is a cohort analysis tool integrated with Illumina Connected Analytics (ICA). ICA Cohorts combines subject- and sample-level metadata, such as phenotypes, diseases, demographics, and biometrics, with molecular data stored in ICA to perform tertiary analyses on selected subsets of individuals.

## Overview Video

This video is an overview of Illumina Connnected Analytics. It walks through a Multi-Omics Cancer workflow that can be found here: [Oncology Walkthrough](https://help.ica.illumina.com/project/p-cohorts/cohorts-walkthrough-cancer)

{% embed url="<https://www.youtube.com/watch?v=wr19Y8BVaQ4&ab_channel=Illumina>" %}
Illumina Connected Analytics: Cohorts Multi-Omic Cancer
{% endembed %}

### Features At-a-glance

* Intuitive UI for selecting subjects and samples to analyze and compare: deep phenotypical and clinical metadata, molecular features including germline, somatic, gene expression.
* Comprehensive, harmonized data model exposed to ICA Base and ICA Bench users for custom analyses.
* Run analyses in ICA Base and ICA Bench and upload final results back into Cohorts for visualization.
* Out-of-the-box statistical analyses including genetic burden tests, GWAS/PheWAS.
* Rich public data sets covering key disease areas to enrich private data analysis.
* Easy-to-use visualizations for gene prioritization and genetic variation inspection.

## Functionality

* [Create a Cohort](https://help.ica.illumina.com/project/p-cohorts/cohorts-create)
* [Import New Samples](https://help.ica.illumina.com/project/p-cohorts/cohorts-import)
* [Prepare Metadata Sheets](https://help.ica.illumina.com/project/p-cohorts/cohorts-metadata)
* [Precomputed GWAS and PheWAS](https://help.ica.illumina.com/project/p-cohorts/cohorts-gwas-phewas)
* [Cohort Analysis](https://help.ica.illumina.com/project/p-cohorts/cohorts-analysis)
* [Compare Cohorts](https://help.ica.illumina.com/project/p-cohorts/cohorts-comparison)
* [Cohorts Data in ICA Base](https://help.ica.illumina.com/project/p-cohorts/cohorts-base)

## Walk-throughs

* [Oncology](https://help.ica.illumina.com/project/p-cohorts/cohorts-walkthrough-cancer)
* [Rare Genetic Disorders](https://help.ica.illumina.com/project/p-cohorts/cohorts-walkthrough-raredisease)

## Public Data Sets

ICA Cohorts contains a variety of freely available data sets covering different disease areas and sequencing technologies. For a list of currently available data, [see here](https://help.ica.illumina.com/project/p-cohorts/cohorts-publicdata).


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